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It contains amiloride and hydrochlorothiazide which work in synergy to provide diuretic effects that lower the blood pressure.

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This medication also reduces extra fluid in the bodyedemacaused by conditions such as heart failureliver diseaseor kidney diseaseThis can lessen symptoms such as shortness of breath or swelling in your ankles or feet.

Pressor aminese.gnorepinephrinepossible decreased response to pressor amines but not sufficient to preclude their use.

This drug may make you dizzyAlcohol or marijuana can make you more dizzyDo not driveuse machineryor do anything that needs alertness until you can do it safelyLimit alcoholic beveragesTalk to your doctor if you are using marijuana.

In published studiesclinically significant hypokalemia has been consistently less common in patients who received 12.5 mg of hydrochlorothiazide than in patients who received higher dosesNeverthelessperiodic determination of serum electrolytes should be performed in patients who may be at risk for the development of hypokalemiaPatients should be observed for signs of fluid or electrolyte disturbancesi.ehyponatremiahypochloremic alkalosisand hypokalemia and hypomagnesemia.

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a search of a drug database shows that a variety of dermatologic or skin reactions can occur with hydrochlorothiazide, including rash.

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